We are delighted to announce the next event in a series of talks presenting University of Cambridge leading research activities to industrial audiences:
From discovery science to industrial applications: Biomicrofabrication of Cellular Interfaces
by Dr Yan Yan Shery Huang, Department of Engineering
20 June 2018, 5 for 5:30pm at the Maxwell Centre
Shery Huang's group 'Biointerface' explores a new generation of tissue engineering constructs for personalised therapy at affordable costs; and aims to provide new solutions for future disease monitoring, drug testing and better patient healthcare.
Based in the Department of Engineering, the group focuses on 3D bioprinting/ bio-microfabrication and developing biomimetic organ-on-chips for high throughput drug testing. The group combines nanotechnology and new material fabrication techniques to construct the defined biochemical and physical inputs of an extracellular matrix (ECM) scaffold. The research is highly multi-disciplinary in nature, crossing fields of engineering, biology, chemistry, polymer physics and computer science. Shery Huang will talk about the group’s work and how it might be applied to industrial processes now and in the future. For further information please see http://www.eng.cam.ac.uk/profiles/yysh2
About the Speaker:
Dr Yan Yan Shery Huang completed her MEng degree in Materials Science and Engineering from Imperial College London in 2007 (1st Class; top of the class for four years). With a Cambridge Gates Scholarship, she then pursued a PhD in Physics at Cambridge, focusing on carbon nanotechnology. Dr Huang was a visiting researcher at University of Texas at Austin (2008). After graduating from her PhD in 2011, she was awarded an Oppenheimer Fellowship and a Homerton College Junior Research Fellowship. Since Aug 2013, she has had a Lectureship in Bioengineering. You can read more about Dr Huang at ''The Meaning of Success: Insights from Women at Cambridge'.
Abstract:
With the push to reduce in vivo approaches, the demand for microphysiological models that recapitulate the in vivo settings in vitro is dramatically increasing. This study presents an extracellular matrix-integrated microfluidic chip with a rounded microvessel of ~100µm in diameter. Our system displays favorable characteristics for broad user adaptation: simplified procedure for vessel creation, minimised use of reagents and cells, and the ability to couple live-cell imaging and image analysis to study dynamics of cell-microenvironment interactions in three dimension. We show how this platform can be used to culture different endothelial cell types, and also to perform cancer transendothelial migration studies. Finally, a new technique will be introduced to enable biofibre patterning in the two-dimensional and three-dimensional formats.
Programme
5.00pm: Registration
5.30pm: Dr Yan Yan Shery Huang “Biomicrofabrication of Cellular Interfaces” followed by Q&As
6.30pm: Networking
7pm: Event closes
Registration
Places are limited, prior booking is essential.
To register please visit https://www.cambridgenetwork.co.uk/events/researchtalk-20jun/.
The talk is organised in collaboration between the Maxwell Centre and Cambridge Network.